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Glutathione peroxidase-1 gene (GPX1) variants, oxidative stress and risk of kidney complications in people with type 1 diabetes.

Metabolism: clinical and experimental - 1 Feb 2016

Mohammedi Kamel, Patente Thiago A, Bellili-Muñoz Naima, Driss Fathi, Le Nagard Hervé, Fumeron Frédéric, Roussel Ronan, Hadjadj Samy, Corrêa-Giannella Maria Lúcia, Marre Michel, Velho Gilberto

Abstract excerpt

BACKGROUND AND AIM: Glutathione peroxidase (GPX) is a class of antioxidant enzymes that catalyze the reduction of hydrogen peroxide to water. GPX1 is the most abundant isoform and is expressed in all kidney cells. Isoprostane and advanced oxidation protein products (AOPP) were identified as markers of oxidative stress in patients with kidney disease. We investigated associations of GPX1 genotypes with kidney...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26773925
DOI: 10.1016/j.metabol.2015.10.004

Genes

GPX1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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