Article
Interplay between Superoxide Dismutase, Glutathione Peroxidase, and Peroxisome Proliferator Activated Receptor Gamma Polymorphisms on the Risk of End-Stage Renal Disease among Han Chinese Patients.
Oxidative medicine and cellular longevity - 1 Jan 2016
Chao Chia-Ter, Chen Yen-Ching, Chiang Chih-Kang, Huang Jenq-Wen, Fang Cheng-Chung, Chang Chen-Chih, Yen Chung-Jen
Abstract excerpt
Background. Single nucleotide polymorphisms (SNPs) of antioxidants, including superoxide dismutase 2 (SOD2) and glutathione peroxidase 1 (GPX1), play an important role in the risk for cancer and metabolic disorders. However, little is known regarding the effect of antioxidant SNPs on renal events. Methods. We prospectively enrolled multicenter patients with end-stage renal disease (ESRD) and those without chronic...
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