Article
Manganese superoxide dismutase (SOD2) polymorphisms, plasma advanced oxidation protein products (AOPP) concentration and risk of kidney complications in subjects with type 1 diabetes.
PloS one - 1 Jan 2014
Mohammedi Kamel, Bellili-Muñoz Naïma, Driss Fathi, Roussel Ronan, Seta Nathalie, Fumeron Frédéric, Hadjadj Samy, Marre Michel, Velho Gilberto
Abstract excerpt
AIMS: Oxidative stress is involved in the pathophysiology of diabetic nephropathy. Manganese superoxide dismutase (SOD2) catalyses the dismutation of superoxide, regulates the metabolism of reactive oxygen species in the mitochondria and is highly expressed in the kidney. Plasma concentration of advanced oxidation protein products (AOPP), a marker of oxidative stress, was found to be increased in patients with...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.