Article
Oxidative Stress Genes in Diabetes Mellitus Type 2: Association with Diabetic Kidney Disease.
Oxidative medicine and cellular longevity - 1 Jan 2021
Roumeliotis Athanasios, Roumeliotis Stefanos, Tsetsos Fotis, Georgitsi Marianthi, Georgianos Panagiotis I, Stamou Aikaterini, Vasilakou Anna, Kotsa Kalliopi, Tsekmekidou Xanthippi, Paschou Peristera, Panagoutsos Stylianos, Liakopoulos Vassilios
Abstract excerpt
Diabetic type 2 patients compared to nondiabetic patients exhibit an increased risk of developing diabetic kidney disease (DKD), the leading cause of end-stage renal disease. Hyperglycemia, hypertension, oxidative stress (OS), and genetic background are some of the mechanisms and pathways implicated in DKD pathogenesis. However, data on OS pathway susceptibility genes show limited success and conflicting or...
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