Article
Involvement of CASP3 promoter polymorphism (-1337 C > G) in the development and progression of non-small cell lung cancer.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jul 2016
Javid Jamsheed, Mir Rashid, Saxena Alpana
Abstract excerpt
Downregulation of CASP3 gene expression has been observed to be associated with various malignancies, and promoter polymorphisms in the CASP3 gene may have a great impact on the CASP3 transcriptional activity. The present study aimed to analyze the possible impact of the CASP3 (-1337 C > G, rs1405937) polymorphism on the expression profile of CASP3 gene and ultimately its association in the development of...
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