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Article

Identification of polymorphisms in the Caspase-3 gene and their association with lung cancer risk.

Molecular carcinogenesis - 1 May 2008

Jang Jin Sung, Kim Kyung Mee, Choi Jin Eun, Cha Sung Ick, Kim Chang Ho, Lee Won Kee, Kam Sin, Jung Tae Hoon, Park Jae Yong

Abstract excerpt

Caspase-3 (CASP-3) is a primary effector CASP that executes programmed cell death, and it plays an important role in the development and progression of cancer. Polymorphisms in the CASP-3 gene may influence CASP-3 production and/or activity, thereby modulating the susceptibility to lung cancer. To test this hypothesis, we first screened for polymorphisms in the CASP-3 gene by direct sequencing of genomic DNA...

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Identifiers

PMID: 18058802
DOI: 10.1002/mc.20397

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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