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Article

Polymorphisms in the caspase genes and the risk of lung cancer.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Aug 2010

Lee Shin Yup, Choi Yi Young, Choi Jin Eun, Kim Min Jung, Kim Jong-Sik, Jung Deuk Kju, Kang Hyo-Gyoung, Jeon Hyo-Sung, Lee Won Kee, Jin Guang, Cha Seung Ick, Kim Chang Ho, Jung Tae Hoon, Park Jae Yong

Abstract excerpt

INTRODUCTION: Caspases (CASPs) are important regulators and executioners in apoptosis pathway and play a crucial role in the development and progression of cancer. On the basis of the interactions of CASPs in the apoptotic pathway, we evaluated the association between 11 polymorphisms of CASP3, 6, 7, 8, 9, and 10 genes and the risk of lung cancer. METHODS: The genotypes were determined in 720 patients with lung...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20661084
DOI: 10.1097/JTO.0b013e3181e04543

Genes

CASP3
CASP7
CASP9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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