Article
HuGE systematic review and meta-analysis demonstrate association of CASP-3 and CASP-7 genetic polymorphisms with cancer risk.
Genetics and molecular research : GMR - 13 May 2013
Yan S, Li Y Z, Zhu X W, Liu C L, Wang P, Liu Y L
Abstract excerpt
Genetic variations in the caspase genes CASP-3 and CASP-7 are known to be involved in apoptosis, cytokine maturation, cell growth and differentiation. Polymorphisms of CASP-3 and CASP-7 genes have been increasingly recognized as important regulators in the development of cancer. However, whether there is a specific association is still controversial. Therefore, we made a Human Genome Epidemiology review and...
Topics
- Caspase 3
- Caspase 7
- Genetic Association Studies
- Genetic Predisposition to Disease
- Genome, Human
- Humans
- Neoplasms
- Polymorphism, Single Nucleotide
- Publication Bias
- Risk Factors