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Article

Caspase 9 promoter polymorphisms and risk of primary lung cancer.

Human molecular genetics - 15 Jun 2006

Park Jae Yong, Park Jung Min, Jang Jin Sung, Choi Jin Eun, Kim Kyung Mee, Cha Sung Ick, Kim Chang Ho, Kang Young Mo, Lee Won Kee, Kam Sin, Park Rang Woon, Kim In San, Lee Jae-Tae, Jung Tae Hoon

Abstract excerpt

Caspase-9 (CASP-9) is an initiator CASP in the apoptosome-driven apoptosis pathway and plays an important role in the development and progression of cancer. Polymorphisms in the promoter region of the CASP-9 gene may influence the promoter activity of this gene, thereby modulating susceptibility to lung cancer. To test this hypothesis, we examined the association of four polymorphisms [-1263A>G, -905T>G, -712C>T...

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PMID: 16687442
DOI: 10.1093/hmg/ddl119

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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