Article
Polymorphisms in the Caspase7 gene and the risk of lung cancer.
Lung cancer (Amsterdam, Netherlands) - 1 Jul 2009
Lee Won Kee, Kim Jong Sik, Kang Hyo-Gyoung, Cha Sung Ick, Kim Dong Sun, Hyun Dae Sung, Kam Sin, Kim Chang Ho, Jung Tae Hoon, Park Jae Yong
Abstract excerpt
BACKGROUND: Caspase7 (CASP7) is an executioner CASP that conducted a coordinated program of proteolysis that results in the destruction of critical cell structures, and it plays an important role in the development and progression of cancer. The purpose of this study is to comprehensively evaluate potential functional polymorphisms in the CASP7 gene in relation to the risk of lung cancer. METHODS: We first...
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