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Article

Quantitative Detection and Resolution of BRAF V600 Status in Colorectal Cancer Using Droplet Digital PCR and a Novel Wild-Type Negative Assay.

The Journal of molecular diagnostics : JMD - 1 Mar 2016

Bidshahri Roza, Attali Dean, Fakhfakh Kareem, McNeil Kelly, Karsan Aly, Won Jennifer R, Wolber Robert, Bryan Jennifer, Hughesman Curtis, Haynes Charles

Abstract excerpt

A need exists for robust and cost-effective assays to detect a single or small set of actionable point mutations, or a complete set of clinically informative mutant alleles. Knowledge of these mutations can be used to alert the clinician to a rare mutation that might necessitate more aggressive clinical monitoring or a personalized course of treatment. An example is BRAF, a (proto)oncogene susceptible to either...

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Identifiers

PMID: 26762843
DOI: 10.1016/j.jmoldx.2015.09.003

Genes

BRAF

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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