Article
Clinical validation and implementation of droplet digital PCR for the detection of BRAF mutations from cell-free DNA.
Pathology - 1 Oct 2022
Arnolda Rainier, Howlett Kerryn, Chan Timmy, Raleigh Jeanette, Hatzimihalis Athena, Bell Anthony, Fellowes Andrew, Sandhu Shahneen, McArthur Grant A, Fox Stephen B, Dawson Sarah-Jane, Hewitt Chelsee, Jones Kate, Wong Stephen Q
Abstract excerpt
Droplet digital PCR (ddPCR) has been demonstrated in many research studies to be a sensitive method in the analysis of circulating tumour DNA (ctDNA) for identifying mutations and tracking disease. The transition of ddPCR into the diagnostic setting requires a number of critical steps including the assessment of accuracy and precision and ultimately implementation into clinical use. Here we present the clinical...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.