Article
Automated PCR detection of BRAF mutations in colorectal adenocarcinoma: a diagnostic test accuracy study.
Journal of clinical pathology - 1 May 2016
Colling Richard, Wang Lai Mun, Soilleux Elizabeth
Abstract excerpt
BACKGROUND: Testing for BRAF mutations in colorectal carcinoma (CRC) is important in the screening pathway for Lynch syndrome and is of prognostic value to guide management. This is a diagnostic accuracy study of the Idylla system, a novel and automated alternative PCR system. METHODS: 100 consecutive formalin-fixed, paraffin-embedded CRC resection cases were tested for BRAF mutations using the Idylla automated...
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