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Article

Association of Butyrylcholinesterase-K Allele and Apolipoprotein E ɛ4 Allele with Cognitive Decline in Dementia with Lewy Bodies and Alzheimer's Disease.

Journal of Alzheimer's disease : JAD - 1 Jan 2016

Vijayaraghavan Swetha, Darreh-Shori Taher, Rongve Arvid, Berge Guro, Sando Sigrid B, White Linda R, Auestad Bjørn H, Witoelar Aree, Andreassen Ole A, Ulstein Ingun D, Aarsland Dag

Abstract excerpt

BACKGROUND: A common polymorphism of the butyrylcholinesterase gene, the K-variant (BCHE-K) is associated with reduced butyrylcholinesterase (BuChE) activity. Insufficient studies exist regarding the frequency and role of BCHE-K in dementias. OBJECTIVE: To determine the association of BCHE-K and APOEɛ4 with diagnosis and rate of cognitive decline in dementia with Lewy bodies (DLB) and Alzheimer's disease (AD)...

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Source

Identifiers

PMID: 26757188
DOI: 10.3233/JAD-150750

Genes

BCHE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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