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Article

Plasma butyrylcholinesterase activity: a possible biomarker for differential diagnosis between Alzheimer's disease and dementia with Lewy bodies?

The International journal of neuroscience - 1 Dec 2017

Josviak N D, Batistela M S, Souza R K M, Wegner N R, Bono G F, Sulzbach C D, Simão-Silva D P, Piovezan M R, Souza R L R, Furtado-Alle L

Abstract excerpt

Butyrylcholinesterase (BChE) is an enzyme encoded by BCHE gene, responsible for secondary hydrolysis of the acetylcholine. K and -116A BCHE variants were associated with decrease in plasma BChE activity, and their influence has been investigated in diseases with a cholinergic deficit such as Alzheimer's disease (AD) and dementia with Lewy bodies (DLB). In order to check the influence of BCHE genetic variants on...

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Identifiers

PMID: 28504037
DOI: 10.1080/00207454.2017.1329203

Genes

BCHE

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Plasma butyrylcholinesterase activity: a possible biomarker for differential diagnosis between Alzheimer's disease and dementia with Lewy bodies?PMID 28504037Read ↗

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