Article
No differences of butyrylcholinesterase protein activity and allele frequency in Lewy body diseases.
Neurobiology of disease - 1 Aug 2009
Maetzler Walter, Keller Stefanie, Michelis Joan, Koehler Niklas, Stransky Elke, Becker Clemens, Schulte Claudia, Melms Arthur, Gasser Thomas, Berg Daniela
Abstract excerpt
Butyrylcholinesterase (BChE) genotypes and protein (BuChE) activity, especially in combination with Apolipoprotein E4 (ApoE4), have been investigated as risk factors for developing Alzheimer disease (AD) and may be associated with the rate of progression of cognitive decline. Despite similar pathologic (e.g. amyloid deposition) and neurochemical (e.g. cholinergic deficits) aspects between AD and Lewy body...
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