Article
Impact of Different Target Sequences on Type III CRISPR-Cas Immunity.
Journal of bacteriology - 11 Jan 2016
Maniv Inbal, Jiang Wenyan, Bikard David, Marraffini Luciano A
Abstract excerpt
UNLABELLED: Clustered regularly interspaced short palindromic repeat (CRISPR) loci encode an adaptive immune system of prokaryotes. Within these loci, sequences intercalated between repeats known as "spacers" specify the targets of CRISPR immunity. The majority of spacers match sequences present in phages and plasmids; however, it is not known whether there are differences in the immunity provided against these...
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