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Article

Sickle haemoglobin, haemoglobin C and malaria mortality feedbacks.

Malaria journal - 12 Jan 2016

Gonçalves Bronner P, Gupta Sunetra, Penman Bridget S

Abstract excerpt

BACKGROUND: Sickle haemoglobin (HbS) and haemoglobin C (HbC) are both caused by point mutations in the beta globin gene, and both offer substantial malaria protection. Despite the fact that the blood disorder caused by homozygosity for HbC is much less severe than that caused by homozygosity for HbS (sickle cell anaemia), it is the sickle mutation which has come to dominate many old-world malarious regions,...

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Identifiers

PMID: 26753833
DOI: 10.1186/s12936-015-1077-5
PMCID: PMC4709991

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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