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Article

Novel Insights Into the Protective Role of Hemoglobin S and C Against Plasmodium falciparum Parasitemia.

The Journal of infectious diseases - 15 Aug 2015

Mangano Valentina D, Kabore Youssouf, Bougouma Edith C, Verra Federica, Sepulveda Nuno, Bisseye Cyrille, Santolamazza Federica, Avellino Pamela, Tiono Alfred B, Diarra Amidou, Nebie Issa, Rockett Kirk A, Sirima Sodiomon B, Modiano David

Abstract excerpt

Although hemoglobin S (HbS) and hemoglobin C (HbC) are well known to protect against severe Plasmodium falciparum malaria, conclusive evidence on their role against infection has not yet been obtained. Here we show, in 2 populations from Burkina Faso (2007-2008), that HbS is associated with a 70%...

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Identifiers

PMID: 25712976
DOI: 10.1093/infdis/jiv098
PMCID: PMC4512610

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25712976-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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