Article
Genome-wide association study identifies variation at 6q25.1 associated with survival in multiple myeloma.
Nature communications - 8 Jan 2016
Johnson David C, Weinhold Niels, Mitchell Jonathan S, Chen Bowang, Kaiser Martin, Begum Dil B, Hillengass Jens, Bertsch Uta, Gregory Walter A, Cairns David, Jackson Graham H, Försti Asta, Nickel Jolanta, Hoffmann Per, Nöethen Markus M, Stephens Owen W, Barlogie Bart, Davis Faith E, Hemminki Kari, Goldschmidt Hartmut, Houlston Richard S, Morgan Gareth J
Abstract excerpt
Survival following a diagnosis of multiple myeloma (MM) varies between patients and some of these differences may be a consequence of inherited genetic variation. In this study, to identify genetic markers associated with MM overall survival (MM-OS), we conduct a meta-analysis of four patient series of European ancestry, totalling 3,256 patients with 1,200 MM-associated deaths. Each series is genotyped for...
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