Article

Germline and somatic genetic effects on gene expression and outcome in patients with Multiple Myeloma

2024-10-13

Abstract excerpt

Multiple Myeloma (MM) is a hematological malignancy associated with poor prognosis and relapses. MM has a strong inherited component, and while the mutational and transcriptomic landscapes of MM have been characterized extensively, the molecular consequences of germline genetic variation in MM have not been previously explored. Here, we have leveraged matched genotype and expression data from 607 patients to map t...

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Literature Corpus work: 0db80172-e6c6-528e-a8c1-c8ccfd423bc8
DOI: 10.1101/2024.10.09.617438

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