Article
MyelomA Genetics International Consortium.
Leukemia & lymphoma - 1 May 2012
Morgan Gareth, Johnsen Hans Erik, Goldschmidt Hartmut, Palumbo Antonio, Cavo Michele, Sonneveld Pieter, Miguel Jesus San, Chim Char Sang, Browne Paul, Einsele Hermann, Waage Anders, Turesson Ingemar, Spencer Andrew, Hajek Roman, Ludwig Heinz, Hemminki Kari, Houlston Richard
Abstract excerpt
While the etiology of multiple myeloma (MM) is largely unknown, evidence for an inherited genetic susceptibility is provided by the two-fold increased risk of the disease seen in first-degree relatives of cases of MM. It is likely that part of this heritable risk is a consequence of the co-inheritance of low-risk genetic variants. The accumulated experience to date in identifying risk variants for other tumors...
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