Article
Inherited genetic susceptibility to multiple myeloma.
Leukemia - 1 Mar 2014
Morgan G J, Johnson D C, Weinhold N, Goldschmidt H, Landgren O, Lynch H T, Hemminki K, Houlston R S
Abstract excerpt
Although the familial clustering of multiple myeloma (MM) supports the role of inherited susceptibility, only recently has direct evidence for genetic predisposition been demonstrated. A meta-analysis of two genome-wide association (GWA) studies has identified single-nucleotide polymorphisms (SNPs) localising to a number of genomic regions that are robustly associated with MM risk. In this review, we provide an...
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