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Article

Association between cancer risk and drug-metabolizing enzyme gene (CYP2A6, CYP2A13, CYP4B1, SULT1A1, GSTM1, and GSTT1) polymorphisms in cases of lung cancer in Japan.

Drug metabolism and pharmacokinetics - 1 Jan 2011

Tamaki Yuichiro, Arai Tomio, Sugimura Haruhiko, Sasaki Takamitsu, Honda Masashi, Muroi Yuka, Matsubara Yoichi, Kanno Shuichi, Ishikawa Masaaki, Hirasawa Noriyasu, Hiratsuka Masahiro

Abstract excerpt

Genetic polymorphisms of enzymes involved in the metabolism of carcinogens are suggested to modify an individual's susceptibility to lung cancer. The purpose of this study was to investigate the relationship between lung cancer cases in Japan and variant alleles of cytochrome P450 (CYP) 2A6 (CYP2A6*4), CYP2A13 (CYP2A13*1-*10), CYP4B1 (CYP4B1*1-*7), sulfotransferase 1A1 (SULT1A1*2), glutathione S-transferase M1...

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Share to Aryl Hydrocarbon Hydroxylases
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21791872
DOI: 10.2133/dmpk.dmpk-11-rg-046

Genes

GSTM1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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