Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of genotypes of carcinogen-metabolizing enzymes and smoking status with bladder cancer in a Japanese population.

Environmental health and preventive medicine - 1 Mar 2013

Cui Xiaoyi, Lu Xi, Hiura Mizue, Omori Hisamitsu, Miyazaki Wataru, Katoh Takahiko

Abstract excerpt

OBJECTIVES: Arylamines are considered to be the primary causative agent of bladder cancer in tobacco smokers. To test the hypothesis that variation in the genes that metabolize tobacco carcinogens contribute to bladder cancer, we examined the effects of single nucleotide polymorphisms in the genes of four key enzymes: cytochrome P450 1A2, N-acetyltransferase (NAT) 2, sulfotransferase 1A1, and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arylamine N-Acetyltransferase
Share to Arylsulfotransferase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carcinoma, Transitional Cell

Share to Cytochrome P-450 CYP1A2

Share to Glucuronosyltransferase

Share to Smoking

Share to Urinary Bladder Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 22961351
DOI: 10.1007/s12199-012-0302-x
PMCID: PMC3590317

Genes

NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of genotypes of carcinogen-metabolizing enzymes and smoking status with bladder cancer in a Japanese population.PMID 22961351Read ↗

Cytochrome P450 (CYP) 1A2, sulfotransferase (SULT) 1A1, and N-acetyltransferase (NAT) 2 polymorphisms and susceptibility to urothelial cancer.Semantic proximity Read ↗

NAT2 gene polymorphism as a possible marker for susceptibility to bladder cancer in Japanese.Semantic proximity Read ↗

Genetic polymorphisms of N-acetyltransferase 1 and 2 and risk of cigarette smoking-related bladder cancer.Semantic proximity Read ↗

Association of NAT2, GSTM1, GSTT1, CYP2A6, and CYP2A13 gene polymorphisms with susceptibility and clinicopathologic characteristics of bladder cancer in Central China.Semantic proximity Read ↗

Tobacco use and occupational exposure to carcinogens, but not N-acetyltransferase 2 genotypes are major risk factors for bladder cancer in the Japanese.Semantic proximity Read ↗

Bladder cancer risk from the perspective of genetic polymorphisms in the carcinogen metabolizing enzymes.Semantic proximity Read ↗

Cytochrome P4501A2 phenotype and bladder cancer risk: The Shanghai bladder cancer study.Semantic proximity Read ↗

N-acetyltransferase 2 polymorphism is associated with bladder cancer risk: An updated meta-analysis based on 54 case-control studies.Semantic proximity Read ↗

Interaction effect in bladder cancer between N-acetyltransferase 2 genotype and alcohol drinking.Semantic proximity Read ↗

Polymorphisms in GSTT1, GSTM1, NAT1 and NAT2 genes and bladder cancer risk in men and women.Semantic proximity Read ↗

Evaluating interactions of polygenic risk scores and NAT2 genotypes with tobacco smoking in bladder cancer risk.Semantic proximity Read ↗

Association Between N-acetyltransferase 2 Polymorphism and Bladder Cancer Risk: Results From Studies of the Past Decade and a Meta-Analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.