Article
Lack of association between smoking and CYP2A6 gene polymorphisms in A Japanese population.
Nihon Arukoru Yakubutsu Igakkai zasshi = Japanese journal of alcohol studies & drug dependence - 1 Oct 2001
Zhang X, Amemo K, Ameno S, Iwahashi K, Kinoshita H, Kubota T, Mostofa J, Ijiri I
Abstract excerpt
This study determined the genotypes of the CYP2A6 gene in 96 smokers and 141 non-smokers in a Japanese population. The frequencies of wild-type of the CYP2A6* 1 and those with a whole deletion of the CYP2A6 gene were 93 (96.9%) and 3 (3.1%) in 96 smokers, and 134 (95.0%) and 7 (5.0%) in non-smokers, respectively. In addition, neither the CYP2A6* 2 nor CYP2A6* 3 alleles were observed in the population studied....
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