Article
CYP2E1 and NQO1 genotypes, smoking and bladder cancer.
Pharmacogenetics - 1 Jun 2003
Choi Ji-Yeob, Lee Kyoung-Mu, Cho Soo-Hun, Kim Soo-Woong, Choi Han-Yong, Lee Sang-Yoon, Im Hyoung-June, Yoon Ki Jung, Choi Hwang, Choi Inmi, Hirvonen Ari, Hayes Richard B, Kang Daehee
Abstract excerpt
BACKGROUND: Cytochrome P450 2E1 (CYP2E1) and NAD(P)H:quinone oxidoreductase (NQO1) catalyze the activation of some environmental procarcinogens present in tobacco smoke (i.e. nitrosoamines and heterocyclic amines). We conducted a hospital based case-control study to evaluate the potential associa...
Topics
- Asian People
- Cytochrome P-450 CYP2E1
- Female
- Genetic Predisposition to Disease
- Genotype
- Humans
- Male
- NAD(P)H Dehydrogenase (Quinone)
- Smoking
- Urinary Bladder Neoplasms