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Article

CYP2E1 and NQO1 genotypes, smoking and bladder cancer.

Pharmacogenetics - 1 Jun 2003

Choi Ji-Yeob, Lee Kyoung-Mu, Cho Soo-Hun, Kim Soo-Woong, Choi Han-Yong, Lee Sang-Yoon, Im Hyoung-June, Yoon Ki Jung, Choi Hwang, Choi Inmi, Hirvonen Ari, Hayes Richard B, Kang Daehee

Abstract excerpt

BACKGROUND: Cytochrome P450 2E1 (CYP2E1) and NAD(P)H:quinone oxidoreductase (NQO1) catalyze the activation of some environmental procarcinogens present in tobacco smoke (i.e. nitrosoamines and heterocyclic amines). We conducted a hospital based case-control study to evaluate the potential association between genetic polymorphisms of CYP2E1 (C1019T in the 5' flanking region) and NQO1 (C609T in exon 6) and bladder...

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Source

Identifiers

PMID: 12777965
DOI: 10.1097/00008571-200306000-00006

Genes

NQO1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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CYP2E1 and NQO1 genotypes, smoking and bladder cancer.PMID 12777965Read ↗

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