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Article

Evaluation of CYP2A6 genetic polymorphisms as determinants of smoking behavior and tobacco-related lung cancer risk in male Japanese smokers.

Carcinogenesis - 1 Dec 2004

Fujieda Masaki, Yamazaki Hiroshi, Saito Tetsuya, Kiyotani Kazuma, Gyamfi Maxwell Afari, Sakurai Masaharu, Dosaka-Akita Hirotoshi, Sawamura Yuichi, Yokota Jun, Kunitoh Hideo, Kamataki Tetsuya

Abstract excerpt

We reported previously that subjects homozygous for the cytochrome P450 2A6 (CYP2A6) (*)4 have a lower risk of lung cancer. The purpose of this study was to clarify whether or not the alterations of smoking behavior and risk for lung cancer could be found in subjects possessing novel CYP2A6 variants discovered recently. An epidemiological study was performed with 1094 cases and 611 controls in male Japanese...

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Identifiers

PMID: 15308589
DOI: 10.1093/carcin/bgh258

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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