Article
Cytochrome P450 2A6 polymorphism in nasopharyngeal carcinoma.
Cancer letters - 8 Sept 2006
Tiwawech Danai, Srivatanakul Petcharin, Karalak Anant, Ishida Takafumi
Abstract excerpt
Nitrosamine has been identified as a carcinogen for nasopharyngeal carcinoma (NPC). Here, we investigated if a nitrosamine metabolizing gene, cytochrome P450 2A6 (CYP2A6) played an important role in NPC development. Relationships between the disease and the CYP2A6 were studied in 74 NPC patients and 137 age-matched healthy controls by using PCR-RFLP assay to distinguish between a wide type allele, *1A, and two...
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