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Article

Neurogranin restores amyloid β-mediated synaptic transmission and long-term potentiation deficits.

Experimental neurology - 1 Mar 2016

Kaleka Kanwardeep Singh, Gerges Nashaat Z

Abstract excerpt

Amyloid β (Aβ) is widely considered one of the early causes of cognitive deficits observed in Alzheimer's disease. Many of the deficits caused by Aβ are attributed to its disruption of synaptic function represented by its blockade of long-term potentiation (LTP) and its induction of synaptic depression. Identifying pathways that reverse these synaptic deficits may open the door to new therapeutic targets. In this...

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Source

Identifiers

PMID: 26721336
DOI: 10.1016/j.expneurol.2015.12.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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