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Article

Growth arrest-specific 1 binds to and controls the maturation and processing of the amyloid-beta precursor protein.

Human molecular genetics - 15 May 2011

Chapuis Julien, Vingtdeux Valérie, Campagne Fabien, Davies Peter, Marambaud Philippe

Abstract excerpt

Alzheimer's disease (AD), the most common neurodegenerative disorder, is characterized by cerebral deposition of amyloid-β (Aβ), a series of peptides derived from the processing of the amyloid-β precursor protein (APP). To identify new candidate genes for AD, we recently performed a transcriptome analysis to screen for genes preferentially expressed in the hippocampus and located in AD linkage regions. This...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21357679
DOI: 10.1093/hmg/ddr085
PMCID: PMC3279048

Genes

APP
CALHM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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