Article
Integrated analyses of a major histocompatibility complex, methylation and transcribed ultra-conserved regions in systemic lupus erythematosus.
International journal of molecular medicine - 1 Jan 2016
Lin Hua, Sui Weiguo, Tan Qiupei, Chen Jiejing, Zhang Yue, Ou Minglin, Xue Wen, Li Fengyan, Cao Cuihui, Sun Yufeng, Dai Yong
Abstract excerpt
Systemic lupus erythematosus (SLE) is a multifactorial autoimmune disease which affects different organs and systems that, has a complex genetic inheritance, and is affected by both epigenetic and environmental risk factors. Previous studies on SLE have lacked the statistical power and genetic resolution to fully determine the influence of major histocompatibility complex (MHC) on SLE. In this study, in order to...
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