Article
Confirmation of five novel susceptibility loci for systemic lupus erythematosus (SLE) and integrated network analysis of 82 SLE susceptibility loci.
Human molecular genetics - 15 Mar 2017
Molineros Julio E, Yang Wanling, Zhou Xu-Jie, Sun Celi, Okada Yukinori, Zhang Huoru, Heng Chua Kek, Lau Yu-Lung, Kochi Yuta, Suzuki Akari, Yamamoto Kazuhiko, Ma Jianyang, Bang So-Young, Lee Hye-Soon, Kim Kwangwoo, Bae Sang-Cheol, Zhang Hong, Shen Nan, Looger Loren L, Nath Swapan K
Abstract excerpt
We recently identified ten novel SLE susceptibility loci in Asians and uncovered several additional suggestive loci requiring further validation. This study aimed to replicate five of these suggestive loci in a Han Chinese cohort from Hong Kong, followed by meta-analysis (11,656 cases and 23,968 controls) on previously reported Asian and European populations, and to perform bioinformatic analyses on all 82...
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