Article
Genome-wide analysis of 5-hmC in the peripheral blood of systemic lupus erythematosus patients using an hMeDIP-chip.
International journal of molecular medicine - 1 May 2015
Sui Weiguo, Tan Qiupei, Yang Ming, Yan Qiang, Lin Hua, Ou Minglin, Xue Wen, Chen Jiejing, Zou Tongxiang, Jing Huanyun, Guo Li, Cao Cuihui, Sun Yufeng, Cui Zhenzhen, Dai Yong
Abstract excerpt
Systemic lupus erythematosus (SLE) is a chronic, potentially fatal systemic autoimmune disease characterized by the production of autoantibodies against a wide range of self-antigens. To investigate the role of the 5-hmC DNA modification with regard to the onset of SLE, we compared the levels 5-h...
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