Article
Advances in lupus genetics and epigenetics.
Current opinion in rheumatology - 1 Sept 2014
Deng Yun, Tsao Betty P
Abstract excerpt
PURPOSE OF REVIEW: Genome-wide association studies have identified more than 50 robust loci associated with systemic lupus erythematosus (SLE) susceptibility, and follow-up studies help reveal candidate causative genetic variants and their biological relevance contributing to the development of SLE. Epigenetic modulation is emerging as an important mechanism for understanding how the implicated genes interact...
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