Article
Isolation of a Hypomorphic skn-1 Allele That Does Not Require a Balancer for Maintenance.
G3 (Bethesda, Md.) - 29 Dec 2015
Tang Lanlan, Dodd William, Choe Keith
Abstract excerpt
In Caenorhabditis elegans, the transcription factor SKN-1 has emerged as a central coordinator of stress responses and longevity, increasing the need for genetic tools to study its regulation and function. However, current loss-of-function alleles cause fully penetrant maternal effect embryonic lethality, and must be maintained with genetic balancers that require careful monitoring and labor intensive strategies...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.