Article
[Meta analysis on the association between parental 5,10-methylenetetrahydrofolate reductase C677T polymorphism and the neural tube defects of their offspring].
Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi - 1 Jan 2011
Liu Tie-cheng, Wang Zhi-ping, Zhao Zhong-tang
Abstract excerpt
OBJECTIVE: To explore the relationship between 5,10-methylenetetrahydrofolate reductase gene polymorphism of the parents and the susceptibility to their offspring having neural tube defects. To forecast and evaluate the onset risk of neural tube defects (NTDs) on the basis of 5,10-methylenetetrah...
Topics
- Gene Frequency
- Genetic Predisposition to Disease
- Genotype
- Humans
- Methylenetetrahydrofolate Reductase (NADPH2)
- Neural Tube Defects
- Parents
- Polymorphism, Genetic
- Risk Factors