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Article

A strong conservative tendency in HBV transcriptase (RT): a majority of natural RT mutations derived from the S gene.

Liver international : official journal of the International Association for the Study of the Liver - 1 Jul 2016

Li Hu, Song Xiao-Fei, Hu Ting-Ting, Ren Hong, Hu Peng

Abstract excerpt

BACKGROUND & AIMS: Little is known about natural mutations in the HBV reverse transcriptase (RT) region. Our study aimed to characterize the natural RT mutation along the natural course of chronic Hepatitis B (CHB). METHODS: Sixty CHB patients (immune-tolerant phase, IT, n = 20; immune-active phase, IA, n = 20 and inactive carriers phase, IC, n = 20) were selected from the Focal study, including 25 subjects with...

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Identifiers

PMID: 26707356
DOI: 10.1111/liv.13051

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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