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Article

Profile of Mutations in the Reverse Transcriptase and Overlapping Surface Genes of Hepatitis B Virus (HBV) in Treatment-Naïve Indonesian HBV Carriers.

Japanese journal of infectious diseases - 22 Nov 2017

Yamani Laura Navika, Yano Yoshihiko, Utsumi Takako, Wasityastuti Widya, Rinonce Hanggoro Tri, Widasari Dewiyani Indah, Juniastuti, Lusida Maria Inge, Soetjipto, Hayashi Yoshitake

Abstract excerpt

Mutations in the reverse transcriptase (RT) region of the hepatitis B virus (HBV) genome are an important factor in low therapeutic effectiveness. Nonetheless, the prevalence of these mutations in HBV strains isolated previously in Indonesia has not been systematically examined. Therefore, in this study, we investigated the profile of mutations in the RT region and the associations of these mutations with amino...

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Identifiers

PMID: 29093313
DOI: 10.7883/yoken.JJID.2017.078

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