Impact of Age at Primary Breast Cancer on Contralateral Breast Cancer Risk in BRCA1/2 Mutation Carriers.

doi:10.1200/JCO.2015.62.3942

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Impact of Age at Primary Breast Cancer on Contralateral Breast Cancer Risk in BRCA1/2 Mutation Carriers.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 10 Feb 2016

van den Broek Alexandra J, van 't Veer Laura J, Hooning Maartje J, Cornelissen Sten, Broeks Annegien, Rutgers Emiel J, Smit Vincent T H B M, Cornelisse Cees J, van Beek Mike, Janssen-Heijnen Maryska L, Seynaeve Caroline, Westenend Pieter J, Jobsen Jan J, Siesling Sabine, Tollenaar Rob A E M, van Leeuwen Flora E, Schmidt Marjanka K

Abstract excerpt

PURPOSE: To determine prospectively overall and age-specific estimates of contralateral breast cancer (CBC) risk for young patients with breast cancer with or without BRCA1/2 mutations. PATIENTS AND METHODS: A cohort of 6,294 patients with invasive breast cancer diagnosed under 50 years of age and treated between 1970 and 2003 in 10 Dutch centers was tested for the most prevalent BRCA1/2 mutations. We report...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age Factors

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to BRCA1 Protein

Share to BRCA2 Protein

Share to Follow-Up Studies

Share to Neoplasm Staging

Share to Neoplasms, Second Primary

Share to Netherlands

Share to Risk Assessment

Source

Open in PubMed

Identifiers

PMID: 26700119
DOI: 10.1200/JCO.2015.62.3942

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Impact of Age at Primary Breast Cancer on Contralateral Breast Cancer Risk in BRCA1/2 Mutation Carriers.PMID 26700119Read ↗

Cumulative risk of second primary contralateral breast cancer in BRCA1/BRCA2 mutation carriers with a first breast cancer: A systematic review and meta-analysis.Semantic proximity Read ↗

Contralateral breast cancer risk in BRCA1 and BRCA2 mutation carriers.Semantic proximity Read ↗

Population-based study of the risk of second primary contralateral breast cancer associated with carrying a mutation in BRCA1 or BRCA2.Semantic proximity Read ↗

Effects of chemotherapy on contralateral breast cancer risk in BRCA1 and BRCA2 mutation carriers: A nationwide cohort study.Semantic proximity Read ↗

The risk of contralateral breast cancer in patients from BRCA1/2 negative high risk families as compared to patients from BRCA1 or BRCA2 positive families: a retrospective cohort study.Semantic proximity Read ↗

Second primary breast cancer in BRCA1 and BRCA2 mutation carriers: 10-year cumulative incidence in the Breast Cancer Family Registry.Semantic proximity Read ↗

High risk of contralateral breast carcinoma in women with hereditary/familial non-BRCA1/BRCA2 breast carcinoma.Semantic proximity Read ↗

Contralateral breast cancer in BRCA1 and BRCA2 mutation carriers.Semantic proximity Read ↗

Triple negative status and BRCA mutations in contralateral breast cancer: a population-based study.Semantic proximity Read ↗

Outcome of conservatively managed early-onset breast cancer by BRCA1/2 status.Semantic proximity Read ↗

Improved overall survival after contralateral risk-reducing mastectomy in BRCA1/2 mutation carriers with a history of unilateral breast cancer: a prospective analysis.Semantic proximity Read ↗

Contralateral breast cancer risk in BRCA1 and BRCA2 mutation carriers in a large cohort of unselected Chinese breast cancer patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.