Article
Triple negative status and BRCA mutations in contralateral breast cancer: a population-based study.
Acta bio-medica : Atenei Parmensis - 6 May 2016
Pellegrino Benedetta, Bella Mariangela, Michiara Maria, Zanelli Paola, Naldi Nadia, Porzio Rosa, Bortesi Beatrice, Boggiani Daniela, Zanoni Daniele, Camisa Roberta, Neri Tauro Maria, Pinto Carmine, Musolino Antonino
Abstract excerpt
BACKGROUND AND AIM OF THE WORK: BRCA1/2 mutation carriers diagnosed with breast cancer have a strong life-time risk of developing contralateral breast cancer (CBC). We performed a population-based study with the aim of estimating the proportion of CBC associated with BRCA1/BRCA2 mutations, and the contribution of germline mutations to both molecular and clinical features of these tumors. METHODS: Fifty-five women...
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