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Article

Second primary breast cancer in BRCA1 and BRCA2 mutation carriers: 10-year cumulative incidence in the Breast Cancer Family Registry.

Breast cancer research and treatment - 1 Jun 2015

Menes Tehillah S, Terry Mary Beth, Goldgar David, Andrulis Irene L, Knight Julia A, John Esther M, Liao Yuyan, Southey Melissa, Miron Alexander, Chung Wendy, Buys Saundra S

Abstract excerpt

BReast CAncer genes 1 and 2 (BRCA1 and BRCA2) mutation carriers diagnosed with breast cancer are at increased risk of developing a second primary breast cancer. Data from high-risk clinics may be subject to different biases which can cause both over and underestimation of this risk. Using data from a large multi-institutional family registry we estimated the 10-year cumulative risk of second primary breast cancer...

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Source

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Identifiers

PMID: 25975955
DOI: 10.1007/s10549-015-3419-y
PMCID: PMC4545282

Genes

BRCA1
BRCA2

Provenance

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