Population-based study of the risk of second primary contralateral breast cancer associated with carrying a mutation in BRCA1 or BRCA2.

doi:10.1200/JCO.2009.24.2495

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Article

Population-based study of the risk of second primary contralateral breast cancer associated with carrying a mutation in BRCA1 or BRCA2.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 10 May 2010

Malone Kathleen E, Begg Colin B, Haile Robert W, Borg Ake, Concannon Patrick, Tellhed Lina, Xue Shanyan, Teraoka Sharon, Bernstein Leslie, Capanu Marinela, Reiner Anne S, Riedel Elyn R, Thomas Duncan C, Mellemkjaer Lene, Lynch Charles F, Boice John D, Anton-Culver Hoda, Bernstein Jonine L

Abstract excerpt

PURPOSE: Women with breast cancer diagnosed early in life comprise a substantial portion of those tested for BRCA1/BRCA2 mutations; however, little information is available on the subsequent risks of contralateral breast cancer in mutation carriers. This study assessed the risk of subsequent contralateral breast cancer associated with carrying a BRCA1 or BRCA2 mutation. PATIENTS AND METHODS: In this nested...

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Identifiers

PMID: 20368571
DOI: 10.1200/JCO.2009.24.2495
PMCID: PMC2881721

Genes

BRCA1
BRCA2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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