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Article

Cumulative risk of second primary contralateral breast cancer in BRCA1/BRCA2 mutation carriers with a first breast cancer: A systematic review and meta-analysis.

Breast (Edinburgh, Scotland) - 1 Dec 2014

Molina-Montes Esther, Pérez-Nevot Beatriz, Pollán Marina, Sánchez-Cantalejo Emilio, Espín Jaime, Sánchez María-José

Abstract excerpt

BRCA1/2 mutation carriers are at a higher risk of breast cancer and of subsequent contralateral breast cancer (CBC). This study aims to evaluate the evidence of the effect of the BRCA1/2-carriership on CBC cumulative risk in female breast cancer patients. The literature was searched in Pubmed and Embase up to June 2013 for studies on CBC risk after a first primary invasive breast cancer in female BRCA1/2 mutation...

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Source

Identifiers

PMID: 25467311
DOI: 10.1016/j.breast.2014.10.005

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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