Article
Outcome of conservatively managed early-onset breast cancer by BRCA1/2 status.
Lancet (London, England) - 27 Apr 2002
Haffty Bruce G, Harrold Elizabeth, Khan Atif J, Pathare Pradip, Smith Tanya E, Turner Bruce C, Glazer Peter M, Ward Barbara, Carter Daryl, Matloff Ellen, Bale Allen E, Alvarez-Franco Mayra
Abstract excerpt
BACKGROUND: Management of early-stage breast cancer in young women with mutations in BRCA1 or BRCA2 remains controversial. This study assessed the long-term risks of ipsilateral and contralateral breast cancer in a cohort of young women who underwent breast-conserving surgery followed by radiotherapy. METHODS: Between 1975 and 1998, 290 women with breast cancer diagnosed at age 42 years or younger underwent...
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