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Article

Generation of longer emission wavelength red fluorescent proteins using computationally designed libraries.

Proceedings of the National Academy of Sciences of the United States of America - 23 Nov 2010

Chica Roberto A, Moore Matthew M, Allen Benjamin D, Mayo Stephen L

Abstract excerpt

The longer emission wavelengths of red fluorescent proteins (RFPs) make them attractive for whole-animal imaging because cells are more transparent to red light. Although several useful RFPs have been developed using directed evolution, the quest for further red-shifted and improved RFPs continues. Herein, we report a structure-based rational design approach to red-shift the fluorescence emission of RFPs. We...

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Identifiers

PMID: 21059931
DOI: 10.1073/pnas.1013910107
PMCID: PMC2996648

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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