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Article

The Eukaryotic Mismatch Recognition Complexes Track with the Replisome during DNA Synthesis.

PLoS genetics - 1 Dec 2015

Haye Joanna E, Gammie Alison E

Abstract excerpt

During replication, mismatch repair proteins recognize and repair mispaired bases that escape the proofreading activity of DNA polymerase. In this work, we tested the model that the eukaryotic mismatch recognition complex tracks with the advancing replisome. Using yeast, we examined the dynamics during replication of the leading strand polymerase Polε using Pol2 and the eukaryotic mismatch recognition complex...

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Source

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Identifiers

PMID: 26684201
DOI: 10.1371/journal.pgen.1005719
PMCID: PMC4684283

Genes

PCNA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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