Determination and Therapeutic Exploitation of Ebola Virus Spontaneous Mutation Frequency.

Abstract excerpt

UNLABELLED: Ebola virus (EBOV) is an RNA virus that can cause hemorrhagic fever with high fatality rates, and there are no approved vaccines or therapies. Typically, RNA viruses have high spontaneous mutation rates, which permit rapid adaptation to selection pressures and have other important biological consequences. However, it is unknown if filoviruses exhibit high mutation frequencies. Ultradeep sequencing and...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Ebolavirus
• Share to Genes, Reporter
• Share to Hemorrhagic Fever, Ebola