Article
Population dynamics of RNA viruses: the essential contribution of mutant spectra.
Archives of virology. Supplementum - 1 Jan 2005
Domingo E, Gonzalez-Lopez C, Pariente N, Airaksinen A, Escarmís C
Abstract excerpt
Cells and their viral and cellular parasites are genetically highly diverse, and their genomes contain signs of past and present variation and mobility. The great adaptive potential of viruses, conferred on them by high mutation rates and quasispecies dynamics, demands new strategies for viral disease prevention and control. This necessitates a more detailed knowledge of viral population structure and dynamics....
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