Article
Rates of spontaneous mutation among RNA viruses.
Proceedings of the National Academy of Sciences of the United States of America - 1 May 1993
Drake J W
Abstract excerpt
Simple methods are presented to estimate rates of spontaneous mutation from mutant frequencies and population parameters in RNA viruses. Published mutant frequencies yield a wide range of mutation rates per genome per replication, mainly because mutational targets have usually been small and, thu...
Topics
- Bacteriophages
- Genome, Viral
- Influenza A virus
- Mathematics
- Models, Genetic
- Mutation
- Poliovirus
- RNA Viruses
- Vesicular stomatitis Indiana virus